Ngwaahịa: 2-phenylacetamide
Usoro ihe omimi: C8H9NO
Arọ molikula: 135.17
Aha Bekee: Phenylacetamide
agwa: kristal dị ọcha ma ọ bụ akwụkwọ.Mp 157-158 ℃, bp 280-290 ℃ (ire ere).Soluble na mmiri ọkụ na ethanol, soluble ntakịrị na mmiri oyi, ether, na benzene.
Ojiji: Ọgwụ dị n'etiti ọgwụ dịka penicillin na phenobarbital.A na-ejikwa ya maka nkwadebe nke phenylacetic acid, ngwa nri, na ọgwụ ndị na-egbu egbu.
Usoro 1) Masuko F, Katsura T.US 4536599A1.1985.
Tinye 117.2 g (1.0 mol) nke phenylacetonitrile (2), 56.1 g nke 25% potassium hydroxide ngwọta, 291.5 g nke 35% hydrogen peroxide aqueous ngwọta, 1.78 g nke benzyltriethylammonium chloride, na 351.5 g nke isopropanol maka mmeghachi omume flax.Tinyegharịa ma meghachi omume na 50 ℃ maka awa 4.Mgbe emechara mmeghachi omume ahụ, a na-ekpochapụ isopropanol n'okpuru nrụgide belatara, mee ka ọ dị mma, kpochaa, jiri mmiri na-asa ya, ma mịrị amị iji nweta onyinye (1) 128.5 g, mp 155 ℃, na mkpụrụ nke 95%.
Usoro 2) Furniss BS, Hannaford AJ, Rogers V, et al.Akwụkwọ ọgụgụ Vogel nke bara uru Chemistry.Longman London na New York. mbipụta nke anọ, 1978：518.
Tinye 100 g (0.85 mol) nke phenylacetonitrile (2) na 400 ml nke hydrochloric acid gbadoro anya na flask mmeghachi omume.N'okpuru edemede, meghachi omume na 40 ℃ maka ihe dị ka nkeji 40, wee bulie okpomọkụ ruo 50 ℃.Gaa n'ihu na-emeghachi omume maka nkeji iri atọ.Jụụ na 15 ℃ ma gbakwunye 400 ml nke mmiri oyi kpọnwụrụ akpọnwụ.Na-ajụ oyi na mmiri ịsa mmiri, na-ehichapụ kristal.Tinye ihe siri ike na 50 ml mmiri ma kpalie nke ọma iji wepụ phenylacetic acid.Nyo na nkụ na 50-80 ℃ iji nweta 95 g nke phenylacetamide (1), mp 154-155 ℃, na mkpụrụ nke 82%.Recrystalization na ethanol, mp 156 ℃.
Oge nzipu: Eprel 11-2023